dedifferentiated liposarcomas with divergent myosarcomatous differentiation
Dedifferentiated liposarcoma (DLPS) is one of the most frequent sarcomas of the retroperitoneum and represents most undifferentiated sarcomas of the internal trunk. In about 5% cases, the dedifferentiated component is an heterologous sarcoma such as leiomyosarcoma or rhabdomyosarcoma.
Most sarcomas with a rhabdomyosarcomatous differentiation occurring in the internal trunk of adults are DLPS. Moreover, DLPS with a myogenic component have a low metastatic potential, similar to conventional DLPS and significantly lower to the metastatic potential of leiomyosarcomas. (#17895758#)
References
Binh MB, Guillou L, Hostein I, Château MC, Collin F, Aurias A, Binh BN, Stoeckle E, Coindre JM. Dedifferentiated liposarcomas with divergent myosarcomatous differentiation developed in the internal trunk: a study of 27 cases and comparison to conventional dedifferentiated liposarcomas and leiomyosarcomas. Am J Surg Pathol. 2007 Oct;31(10):1557-66.PMID: #17895758#
Shimada S, Ishizawa T, Ishizawa K, Kamada K, Hirose T. Dedifferentiated liposarcoma with rhabdomyoblastic differentiation. Virchows Arch. 2005 Nov;447(5):835-41. PMID: #16012847#