papillary renal cell carcinoma with lipocyte-like cells
Papillary renal cell carcinoma (PRCC) is the second most common carcinoma of the kidney, which is classified into two types.
Type 1 displays single layer of cells with scanty pale cytoplasm and type 2 has pseudostratified high-grade nuclei with eosinophilic cytoplasm.
Recently, apart from these two types, oncocytic PRCC and clear-cell PRCC have been described.
Lipocyte-like cells might represent a special type of PRCC or this feature may be an indication of poor prognosis regarding its association with sarcomatoid change.
References
Papillary renal cell carcinoma with lipocyte-like cells: a rare morphological variant or an indication of aggressiveness? Sari A, Evcim G, Ermete M, Bal K, Bolukbasi A. Indian J Pathol Microbiol. 2010 Jul-Sep;53(3):547-9. PMID: #20699521# (Free)