viral cytopathic effects

Types

 viral inclusions

• nuclear viral inclusions
  • cytomegalic inclusions (CMV inclusion)

• cytoplasmic viral inclusions

 multinucleation
 dog ear proerythroblasts : parvovirus B19
 koilocytosis : HPV Human papillomavirus
 decoy cells : BK virus in immunocompromised / transplant patients
 demyelination with enlarged oligodendrocytes : JC Virus
 ground glass hepatocytes : hepatitis B virus HBV
 multinucleated cells with intranuclear Cowdry inclusions : HSV Herpesvirus simplex
 Downey cells / atypical lymphocytes : EBV
 cells with increased size and cytoplasmic granular and nuclear inclusions : CMV
 Kapsoi sarcoma : HHV8
 Guarneri bodies : variola / small pox
 cytoplasmic eosinophilic inclusions in umbilcated skin lesions / epidermal crateriform anomalies : molluscum contagiosum
 blast cells with flower shaped nuclei : HTLV
 Warthin-Finkedley cells : measles
 Negri bodies

Examples

 viral cytopathic changes in CMV gastritis

• https://twitter.com/ARP_Press/status/848302033828552704

 viral inclusions
 herpes esophagitis

• https://twitter.com/AlswiedPath/status/1206245095227265024

References

 Pranav Patwardhan