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nail genetic diseases

Hair and nail development have many similarities and are likely to share many developmental pathways. This is evident from the ectodermal dysplasias that affect both appendages. Of special interest are syndromic disorders as they show the effects of disturbances in molecular pathways that are essential for normal embryonic development.

References

- van Steensel MA, van Geel M, Steijlen PM. Molecular genetics of hereditary hair and nail disease. Am J Med Genet. 2004 Nov 15;131C(1):52-60. PMID: #15468149#