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small HSPs

Small heat shock protein family

Pathology

- HSPB1 mutations in axonal Charcot-Marie-Tooth disease type 2F (MIM.606595)
- HSPB1 mutations in distal hereditary motor neuropathy (MIM.608634)
- HSPB8 mutations in autosomal dominant distal hereditary motor neuropathy type II (MIM.158590)

References

- Der Perng M, Quinlan RA. Neuronal diseases: small heat shock proteins calm your nerves. Curr Biol. 2004 Aug 10;14(15):R625-6. PMID: #15296780#

- Head MW, Goldman JE. Small heat shock proteins, the cytoskeleton, and inclusion body formation. Neuropathol Appl Neurobiol. 2000 Aug;26(4):304-12. PMID: #10931363#

- Clark JI, Muchowski PJ. Small heat-shock proteins and their potential role in human disease. Curr Opin Struct Biol. 2000 Feb;10(1):52-9. PMID: #10679464#