Home > E. Pathology by systems > Locomotory system > Joints > tophus
tophus
Thursday 23 June 2011
gouty tophus; tophi; dermal urate deposits
Digital slides
UI:859 - Interphalangeal joint of toe - Gout tophus.
Images
Tophi in Sesamoid Bone of Foot in gout by Ed Euthman.
Deposits of destroyed uric acid crystals seen as amorphus eosinophilic material in gout
- https://twitter.com/Valdebran/status/748320406440800257
- https://twitter.com/mjcascio/status/748403579912753152
- https://twitter.com/PathAssistant/status/695347222095880192
- https://twitter.com/DanglisFotiosMD/status/875232233187139585
Synopsis
The tophus represents an accumulation of monosodium urate derived from chronic hyperurecemia seen in the disorder called gout.
Surrounding chronic inflammatory cells, fibrosis, and foreign body giant cells can be noted.
Localisation
cutaneous tophus
synovial tophus
See also
dermal urate deposits / urate crystals
gout
uric acid (urate )
deposits
gout