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CPEBs
Friday 18 September 2015
Cytoplasmic polyadenylation elements (CPEs) are located in the 3-prime UTRs of hundreds of mRNAs involved in cell proliferation, chromosome segregation, and cell differentiation. CPEs function as docking sites for CPE-binding proteins (CPEBs), which can either repress or activate mRNA translation. CPEB4 activates mRNA translation by adding poly(A) tails to target mRNAs (Ortiz-Zapater et al., 2012).
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CPEB4
- CPEB4 activates mRNA translation by adding poly(A) tails to target mRNAs (Ortiz-Zapater et al., 2012).