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columnar cell lesion with atypia

Wednesday 14 October 2020

Synopsis

 enlarged acini
 dilated acini
 globoid appearance of the dilated acini
 dilated acini contain secretions
 dilated acini are lined by cells with rounded nuclei with
an increased nuclear to cytoplasmic ratio
 The acini are lined by several layers of luminal epithelial cells with loss of a polar arrangement.
 myoepithelial cells are present, but not prominent.
 Apocrine snouts are observed in most acini.
 conspicuous absence of architectural features diagnostic of ADH as cribriform spaces, bars, or bulbous papillae.

See also

 mammary anomalies